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Fluid Physics and Macromolecular Crystal Growth in MicrogravityThe molecular structure of biological macromolecules is important in understanding how these molecules work and has direct application to rational drug design for new medicines and for the improvement and development of industrial enzymes. In order to obtain the molecular structure, large, well formed, single macromolecule crystals are required. The growth of macromolecule crystals is a difficult task and is often hampered on the ground by fluid flows that result from the interaction of gravity with the crystal growth process. One such effect is the bulk movement of the crystal through the fluid due to sedimentation. A second is buoyancy driven convection close to the crystal surface. On the ground the crystallization process itself induces both of these flows.
Document ID
20000105166
Document Type
Preprint (Draft being sent to journal)
Authors
Pusey, M.
(NASA Marshall Space Flight Center Huntsville, AL United States)
Snell, E.
(NASA Marshall Space Flight Center Huntsville, AL United States)
Judge, R.
(NASA Marshall Space Flight Center Huntsville, AL United States)
Chayen, N.
(Imperial Coll. of Science, Technology and Medicine London, United Kingdom)
Boggon, T.
(Manchester Univ. United Kingdom)
Helliwell, J.
(Manchester Univ. United Kingdom)
Rose, M. Franklin
Date Acquired
August 19, 2013
Publication Date
January 1, 2000
Subject Category
Solid-State Physics
Meeting Information
Meeting: Microgravity Fluid Physics and Transport Phenomena
Location: Cleveland, OH
Country: United States
Start Date: August 10, 2000
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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