NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
A Compact X-Ray System for Support of High Throughput CrystallographyStandard x-ray systems for crystallography rely on massive generators coupled with optics that guide X-ray beams onto the crystal sample. Optics for single-crystal diffractometry include total reflection mirrors, polycapillary optics or graded multilayer monochromators. The benefit of using polycapillary optic is that it can collect x-rays over tile greatest solid angle, and thus most efficiently, utilize the greatest portion of X-rays emitted from the Source, The x-ray generator has to have a small anode spot, and thus its size and power requirements can be substantially reduced We present the design and results from the first high flux x-ray system for crystallography that combine's a microfocus X-ray generator (40microns FWHM Spot size at a power of 45 W) and a collimating, polycapillary optic. Diffraction data collected from small test crystals with cell dimensions up to 160A (lysozyme and thaumatin) are of high quality. For example, diffraction data collected from a lysozyme crystal at RT yielded R=5.0% for data extending to 1.70A. We compare these results with measurements taken from standard crystallographic systems. Our current microfocus X-ray diffraction system is attractive for supporting crystal growth research in the standard crystallography laboratory as well as in remote, automated crystal growth laboratory. Its small volume, light-weight, and low power requirements are sufficient to have it installed in unique environments, i.e.. on-board International Space Station.
Document ID
20010079108
Acquisition Source
Marshall Space Flight Center
Document Type
Conference Paper
Authors
Ciszak, Ewa
(NASA Marshall Space Flight Center Huntsville, AL United States)
Gubarev, Mikhail
(NASA Marshall Space Flight Center Huntsville, AL United States)
Gibson, Walter M.
(State Univ. of New York Albany, NY United States)
Joy, Marshall K.
(NASA Marshall Space Flight Center Huntsville, AL United States)
Whitaker, Ann F.
Date Acquired
August 20, 2013
Publication Date
January 1, 2001
Subject Category
Electronics And Electrical Engineering
Meeting Information
Meeting: European Crystallographic Meeting
Location: Cracow
Country: Poland
Start Date: August 25, 2001
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

Available Downloads

There are no available downloads for this record.
No Preview Available