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Rheoencephalographic (REG) Assessment of Head and Neck Cooling for use with Multiple Sclerosis PatientsWe have prepared a computer program (RHEOSYS:RHEOencephalographic impedance trace scanning SyStem) that can be used to automate the analysis of segmental impedance blood flow waveforms. This program was developed to assist in the post test analysis of recorded impedance traces from multiple segments of the body. It incorporates many of the blood flow, segmental volume, and vascular state indices reported in the world literature. As it is currently programmed, seven points are selected from each blood flow pulse and associated ECG waveforrn: 1. peak of the first ECG QRS complex, 2. start of systolic slope on the blood flow trace, 3. maximum amplitude of the impedance pulse, 4. position of the dicrotic notch, 5. maximum amplitude of the postdicrotic segment, 6. peak of the second ECG QRS complex, and 7. start of the next blood flow pulse. These points we used to calculate various geometric, area, and time-related values associated with the impedance pulse morphology. RHEOSYS then calculates a series of 34 impedance and cardiac cycle parameters which include pulse amplitudes; areas; pulse propagation times; cardiac cycle times; and various measures of arterial and various tone, contractility, and pulse volume. We used this program to calculate the scalp and intracranial blood flow responses to head and neck cooling as it may be applied to lower the body temperatures of multiple sclerosis patients. Twelve women and twelve men were tested using a commercially available head and neck cooling system operated at its maximum cooling capacity for a period of 30 minutes. Head and neck cooling produced a transient change in scalp blood flow and a significant, (P<0.05) decrease of approx. 30% in intracranial blood flow. Results of this experiment will illustrate how REG and RHEOSYS can be used in biomedical applications.
Document ID
20020039617
Acquisition Source
Ames Research Center
Document Type
Conference Paper
Authors
Montogomery, Leslie D.
(Bionetics Corp. Moffett Field, CA United States)
Ku, Yu-Tsuan E.
(Bionetics Corp. Moffett Field, CA United States)
Webbon, Bruce W.
Date Acquired
August 20, 2013
Publication Date
January 1, 1995
Subject Category
Aerospace Medicine
Meeting Information
Meeting: IX International Conference on Electrical Bio-Impedance
Location: Heidelberg
Country: Germany
Start Date: September 26, 1995
End Date: September 30, 1995
Funding Number(s)
PROJECT: RTOP 199-61-62
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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