NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
National Institutes of Health, Rodent 4 (NIH.R4); Calcium Metabolism and Vascular Function After Spaceflight: A Collaborative Series with NASA and NIHThe NIH.R4 payload was a collaborative experiment conducted by NASA's Ames Research Center in conjunction with the National Institutes of Health (NIH). This middeck payload was the fourth in a series of experiments focusing on developmental biology and the effects of microgravity on mammalian systems. The NIH.R4 payload was flown onboard STS-80, which launched November 19, 1996, and landed at Kennedy Space Center on December 7, 1996, and was the longest shuttle mission to date. Fourteen male Spontaneously Hypertensive rats (SHR) were flown; seven in each of two Animal Enclosure Modules (AEM) in the shuttle middeck. The flight animals were exposed to 18 days of microgravity. Two synchronous control groups were utilized for this study in addition to an asynchronous post-flight AEM control study conducted at the PI lab. The animals were fed two different calcium diets in the NASA food bar (2.0% and 0.2%) three weeks prior to launch and insight. Blood pressures were taken at pre-determined intervals and were the basis for flight selection. Upon recovery Dwight animals blood pressure was measured and a variety of tissues were collected. Project testing and data will be presented.
Document ID
20020048133
Acquisition Source
Ames Research Center
Document Type
Preprint (Draft being sent to journal)
Authors
Reiss-Bubenheim, Debra
(NASA Ames Research Center Moffett Field, CA United States)
Steele, Marianne
(Lockheed Martin Engineering and Science Services Moffett Field, CA United States)
Aquillina, Rudy
(Lockheed Martin Engineering and Science Services Moffett Field, CA United States)
Savage, Paul D.
Date Acquired
August 20, 2013
Publication Date
January 1, 1997
Subject Category
Life Sciences (General)
Meeting Information
Meeting: American Society for Gravitational and Space Biology (ASGSB)
Location: Washington, DC
Country: United States
Start Date: November 19, 1997
End Date: November 22, 1997
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

Available Downloads

There are no available downloads for this record.
No Preview Available