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Pentopyranosyl Oligonucleotide SystemsBeta-D-Xylopyranosyl-(4 - 2 )-oligonucleotides containing adenine and thymine as nucleohases were synthesized as a part of a systematic study of the pairing properties of pentopyranosyl oligonucleotides. Contrary to earlier expectations based on qualitative conformational criteria, Beta-D-xylopyranosyl(4 - 2 )- oligonucleotides show Watson-Crick pairing comparable in strength to that shown by pyranosyl-RNA.
Document ID
20030067972
Acquisition Source
Headquarters
Document Type
Reprint (Version printed in journal)
Authors
Wagner, Thomas
(Scripps Research Inst. La Jolla, CA, United States)
Huyuh, Hoan K.
(Scripps Research Inst. La Jolla, CA, United States)
Krishnamurthy, Ramanarayanan
(Eidgenoessische Technische Hochschule Zurich, Switzerland)
Eschenmoser, Albert
(Eidgenoessische Technische Hochschule Zurich, Switzerland)
Date Acquired
August 21, 2013
Publication Date
January 1, 2002
Publication Information
Publication: Helvetica Chimica Acta
Volume: 85
Subject Category
Inorganic, Organic And Physical Chemistry
Funding Number(s)
CONTRACT_GRANT: NAG5-4546
Distribution Limits
Public
Copyright
Other

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