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Removal of Biologically Active Organic Contaminants using Atomic OxygenBiomedical devices that are to come into contact with living tissue, such as prosthetic and other implants for the human body and the containers used to store and transport them, are together cleaned of non-living, but biologically active organic materials, including endotoxins such as lipopolysaccharides, and assembled into a hermetically sealed package without recontamination. This is achieved by cleaning both the device and package components together in an apparatus, which includes a hermetically sealed chamber, in which they are contacted with atomic oxygen which biocleans them, by oxidizing the biologically active organic materials. The apparatus also includes means for manipulating the device and container and hermetically sealing the cleaned device into the cleaned container to form the package. A calibrated witness coupon visually indicates whether or not the device and container have received enough exposure to the atomic oxygen to have removed the organic materials from their surfaces. Gamma radiation is then used to sterilize the device in the sealed container.
Document ID
20030068889
Acquisition Source
Glenn Research Center
Document Type
Other - Patent
External Source(s)
LEW-161871-1
Authors
Bruce A Banks
(Glenn Research Center Cleveland, United States)
Michael A Banks
(Glenn Research Center Cleveland, United States)
Eric B Banks
(Glenn Research Center Cleveland, United States)
Date Acquired
August 21, 2013
Publication Date
May 6, 2003
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
Patent
US-Patent-6,558,621
Patent Application
US-Patent-Appl-SN-606227
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