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New optical scheme for a polarimetric-based glucose sensorA new optical scheme to detect glucose concentration in the aqueous humor of the eye is presented. The ultimate aim is to apply this technique in designing a new instrument for, routinely and frequently, noninvasively monitoring blood glucose levels in diabetic patients without contact (no index matching) between the eye and the instrument. The optical scheme exploits the Brewster reflection of circularly polarized light off of the lens of the eye. Theoretically, this reflected linearly polarized light on its way to the detector is expected to rotate its state of polarization, owing to the presence of glucose molecules in the aqueous humor of a patient's eye. An experimental laboratory setup based on this scheme was designed and tested by measuring a range of known concentrations of glucose solutions dissolved in water. (c) 2004 Society of Photo-Optical Instrumentation Engineers.
Document ID
20040087418
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Ansari, Rafat R.
(NASA Glenn Research Center Cleveland OH United States)
Bockle, Stefan
Rovati, Luigi
Date Acquired
August 21, 2013
Publication Date
January 1, 2004
Publication Information
Publication: Journal of biomedical optics
Volume: 9
Issue: 1
ISSN: 1083-3668
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Other
Keywords
Evaluation Studies
Validation Studies

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