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Automated quantification of mitral valve regurgitation based on normalized centerline velocity distributionPrevious echocardiographic techniques for quantifying valvular regurgitation are limited by factors including uncertainties for orifice location and a hemispheric convergence assumption that often results in over- and underestimation of flow rate and regurgitant orifice area. Using computational fluid dynamics simulations, these factors were eliminated, allowing a more accurate assessment of regurgitation. A model was developed to allow automated quantification of regurgitant orifice diameter based on the centerline velocity data available from color M-mode echocardiography. The model, validated using in vitro unsteady flow data, demonstrated improved accuracy for orifice diameter (y=0.95x + 0.38, r=0.96) and volume (y=1.18x - 4.72, r=0.93).
Document ID
20040087465
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Deserranno, D.
(The Cleveland Clinic Foundation Cleveland, Ohio, United States)
Greenberg, N. L.
Thomas, J. D.
Garcia, M. J.
Date Acquired
August 21, 2013
Publication Date
January 1, 2001
Publication Information
Publication: Computers in cardiology
Volume: 28
ISSN: 0276-6574
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Other
Keywords
NASA Program Biomedical Research and Countermeasures
Validation Studies
Evaluation Studies
NASA Discipline Cardiopulmonary
Non-NASA Center

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