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Mechanics of vimentin intermediate filamentsIt is increasingly evident that the cytoskeleton of living cells plays important roles in mechanical and biological functions of the cells. Here we focus on the contribution of intermediate filaments (IFs) to the mechanical behaviors of living cells. Vimentin, a major structural component of IFs in many cell types, is shown to play an important role in vital mechanical and biological functions such as cell contractility, migration, stiffness, stiffening, and proliferation.
Document ID
20040087665
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Wang, Ning
(Harvard School of Public Health 665 Huntington Ave., Boston, MA 02115, United States)
Stamenovic, Dimitrijie
Date Acquired
August 21, 2013
Publication Date
January 1, 2002
Publication Information
Publication: Journal of muscle research and cell motility
Volume: 23
Issue: 6-May
ISSN: 0142-4319
Subject Category
Life Sciences (General)
Funding Number(s)
CONTRACT_GRANT: HL-33009
Distribution Limits
Public
Copyright
Other
Keywords
Review
Non-NASA Center
Review, Tutorial
NASA Discipline Cell Biology
NASA Program Fundamental Space Biology

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