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Record 55 of 564
Geometric differences of the mitral apparatus between ischemic and dilated cardiomyopathy with significant mitral regurgitation: real-time three-dimensional echocardiography study
External Online Source: doi:10.1161/01.CIR.0000053558.55471.2D
Author and Affiliation:
Kwan, Jun(The Cleveland Clinic Foundation, Cardiovascular Imaging Center, Department of Cardiovascular Medicine, Cleveland, Ohio 44195, United States)
Shiota, Takahiro
Agler, Deborah A.
Popovic, Zoran B.
Qin, Jian Xin
Gillinov, Marc A.
Stewart, William J.
Cosgrove, Delos M.
McCarthy, Patrick M.
Thomas, James D.
Abstract: BACKGROUND: This study was conducted to elucidate the geometric differences of the mitral apparatus in patients with significant mitral regurgitation caused by ischemic cardiomyopathy (ICM-MR) and by idiopathic dilated cardiomyopathy (DCM-MR) by use of real-time 3D echocardiography (RT3DE). METHODS AND RESULTS: Twenty-six patients with ICM-MR caused by posterior infarction, 18 patients with DCM-MR, and 8 control subjects were studied. With the 3D software, commissure-commissure plane and 3 perpendicular anteroposterior (AP) planes were generated for imaging the medial, central, and lateral sides of the mitral valve (MV) during mid systole. In 3 AP planes, the angles between the annular plane and each leaflet (anterior, Aalpha; posterior, Palpha) were measured. In ICM-MR, Aalpha measured in the medial and central planes was significantly larger than that in the lateral plane (39+/-5 degrees, 34+/-6 degrees, and 27+/-5 degrees, respectively; P<0.01), whereas Palpha showed no significant difference in any of the 3 AP planes (61+/-7 degrees, 57+/-7 degrees, and 56+/-7 degrees, P>0.05). In DCM-MR, both Aalpha (38+/-8 degrees, 37+/-9 degrees, and 36+/-7 degrees, P>0.05) and Palpha (59+/-6 degrees, 58+/-5 degrees, and 57+/-6 degrees, P>0.05) revealed no significant differences in the 3 planes. CONCLUSIONS: The pattern of MV deformation from the medial to the lateral side was asymmetrical in ICM-MR, whereas it was symmetrical in DCM-MR. RT3DE is a helpful tool for differentiating the geometry of the mitral apparatus between these 2 different types of functional mitral regurgitation.
Publication Date: Mar 04, 2003
Document ID:
20040087811
(Acquired Sep 07, 2004)
Subject Category: LIFE SCIENCES (GENERAL)
Document Type: Journal Article
Publication Information: Circulation (ISSN 0009-7322); Volume 107; 8; 1135-40
Publisher Information: United States
Organization Source: Real-time three-dimensional echocardiography study
Description: In English
Distribution Limits: Unclassified; Publicly available; Unlimited
Rights: Copyright
NASA Terms: ECHOCARDIOGRAPHY; HEART DISEASES; HEART FUNCTION; HEART VALVES; ISCHEMIA; REAL TIME OPERATION; ADULTS; CARDIAC VENTRICLES; ETIOLOGY; FEMALES; MALES; MYOCARDIUM
Other Descriptors: CARDIOMYOPATHY, CONGESTIVE/COMPLICATIONS; ECHOCARDIOGRAPHY, THREE-DIMENSIONAL/METHODS; MITRAL VALVE/ANATOMY & HISTOLOGY/ULTRASONOGRAPHY; MITRAL VALVE INSUFFICIENCY/ETIOLOGY/ULTRASONOGRAPHY; MYOCARDIAL ISCHEMIA/COMPLICATIONS; COMPARATIVE STUDY; ECHOCARDIOGRAPHY, DOPPLER, COLOR; FEMALE; HEART VENTRICLES/ANATOMY & HISTOLOGY/ULTRASONOGRAPHY; HUMAN; MALE; MIDDLE AGED; MYOCARDIAL DISEASES/COMPLICATIONS; SUPPORT, U.S. GOV'T, NON-P.H.S; VENTRICULAR DYSFUNCTION, LEFT/ULTRASONOGRAPHY; EVALUATION STUDIES; NASA DISCIPLINE CARDIOPULMONARY; NON-NASA CENTER
Availability Source: Other Sources
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