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Paralysis recovery in humans and model systemsConsiderable evidence now demonstrates that extensive functional and anatomical reorganization following spinal cord injury occurs in centers of the brain that have some input into spinal motor pools. This is very encouraging, given the accumulating evidence that new connections formed across spinal lesions may not be initially functionally useful. The second area of advancement in the field of paralysis recovery is in the development of effective interventions to counter axonal growth inhibition. A third area of significant progress is the development of robotic devices to quantify the performance level of motor tasks following spinal cord injury and to 'teach' the spinal cord to step and stand. Advances are being made with robotic devices for mice, rats and humans.
Document ID
20040087930
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Edgerton, V. Reggie
(Los Angeles Brain Research Institute 695 Charles E Young Drive, South Los Angeles 90095-1761, United States)
Roy, Roland R.
Date Acquired
August 21, 2013
Publication Date
December 1, 2002
Publication Information
Publication: Current opinion in neurobiology
Volume: 12
Issue: 6
ISSN: 0959-4388
Subject Category
Cybernetics, Artificial Intelligence And Robotics
Funding Number(s)
CONTRACT_GRANT: NS16333
Distribution Limits
Public
Copyright
Other
Keywords
Review
NASA Discipline Musculoskeletal
Non-NASA Center
Review, Tutorial

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