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Signal averaging technique for noninvasive recording of late potentials in patients with coronary artery diseaseAn advanced non invasive signal averaging technique was used to detect late potentials in two groups of patients: Group A (24 patients) with coronary artery disease (CAD) and without sustained ventricular tachycardia (VT) and Group B (8 patients) with CAD and sustained VT. Recorded analog data were digitized and aligned using a cross correlation function with fast Fourier transform schema, averaged and band pass filtered between 60 and 200 Hz with a non-recursive digital filter. Averaged filtered waveforms were analyzed by computer program for 3 parameters: (1) filtered QRS (fQRS) duration (2) interval between the peak of the R wave peak and the end of fQRS (R-LP) (3) RMS value of last 40 msec of fQRS (RMS). Significant change was found between Groups A and B in fQRS (101 -/+ 13 msec vs 123 -/+ 15 msec; p < .0005) and in R-LP vs 52 -/+ 11 msec vs 71-/+18 msec, p <.002). We conclude that (1) the use of a cross correlation triggering method and non-recursive digital filter enables a reliable recording of late potentials from the body surface; (2) fQRS and R-LP durations are sensitive indicators of CAD patients susceptible to VT.
Document ID
Document Type
Reprint (Version printed in journal)
Abboud, S.
(Boston University School of Medicine United States)
Blatt, C. M.
Lown, B.
Graboys, T. B.
Sadeh, D.
Cohen, R. J.
Date Acquired
August 21, 2013
Publication Date
January 1, 1987
Publication Information
Publication: Computers in cardiology
Volume: 13
ISSN: 0276-6574
Subject Category
Life Sciences (General)
Funding Number(s)
CONTRACT_GRANT: F3361584C0-601
CONTRACT_GRANT: N0001480C0-520
Distribution Limits
NASA Discipline Cardiopulmonary
Non-NASA Center

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