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Transfer function analysis of the autonomic response to respiratory activity during random interval breathingWe report a new method for the noninvasive characterization of the frequency response of the autonomic nervous system (ANS) in mediating fluctuations in heart rate (HR). The approach entails computation of the transfer function magnitude and phase between instantaneous lung volume and HR. Broad band fluctuations in lung volume were initiated when subjects breathed on cue to a sequence of beeps spaced randomly in time. We studied 10 subjects in both supine and standing positions. The transfer function, averaged among all the subjects, showed systematic differences between the two postures, reflecting the differing frequency responses of the sympathetic and parasympathetic divisions of the ANS.
Document ID
20040089154
Acquisition Source
Glenn Research Center
Document Type
Reprint (Version printed in journal)
Authors
Chen, M. H.
(Harvard-MIT Division of Health Sciences and Technology Cambridge, Massachusetts, United States)
Berger, R. D.
Saul, J. P.
Stevenson, K.
Cohen, R. J.
Date Acquired
August 21, 2013
Publication Date
January 1, 1987
Publication Information
Publication: Computers in cardiology
Volume: 13
ISSN: 0276-6574
Subject Category
Life Sciences (General)
Funding Number(s)
CONTRACT_GRANT: F3361584C0-601
CONTRACT_GRANT: N001480C0-520
CONTRACT_GRANT: NAG3-27
Distribution Limits
Public
Copyright
Other
Keywords
Non-NASA Center
NASA Discipline Cardiopulmonary

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