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Invited review: what do we know about the effects of spaceflight on bone?This review of the peer-reviewed literature focuses on the effects of spaceflight on bone. Studies performed in humans and laboratory animals have revealed abnormalities in bone and mineral metabolism that suggest that long-duration spaceflight will have detrimental effects on the skeleton. However, because of large gaps in our knowledge, it is not presently possible to estimate the magnitude of the health risk, individual variations in risk, effective countermeasures, or mechanism(s) of action. Specific recommendations are made for future research to ascertain risk and develop appropriate countermeasures.
Document ID
20040141458
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Turner, R. T.
(Mayo Clinic Rochester, MN 55905, United States)
Date Acquired
August 22, 2013
Publication Date
August 1, 2000
Publication Information
Publication: Journal of applied physiology (Bethesda, Md. : 1985)
Volume: 89
Issue: 2
ISSN: 8750-7587
Subject Category
Aerospace Medicine
Report/Patent Number
ISSN: 8750-7587
Distribution Limits
Public
Copyright
Other
Keywords
NASA Discipline Musculoskeletal
Non-NASA Center
Review, Tutorial
Review
Bone and Bones/anatomy & histology/metabolism/physiology
Weightlessness/adverse effects
Space Flight
Support, U.S. Gov't, Non-P.H.S
Weightlessness Countermeasures
Human
Animals
Support, Non-U.S. Gov't

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