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Multimodality stereotactic brain tissue identification: the NASA smart probe projectReal-time tissue identification can benefit procedures such as stereotactic brain biopsy, functional neurosurgery and brain tumor excision. Optical scattering spectroscopy has been shown to be effective at discriminating cancer from noncancerous conditions in the colon, bladder and breast. The NASA Smart Probe extends the concept of 'optical biopsy' by using neural network techniques to combine the output from 3 microsensors contained within a cannula 2. 7 mm in diameter (i.e. the diameter of a stereotactic brain biopsy needle). Experimental data from 5 rats show the clear differentiation between tissues such as brain, nerve, fat, artery and muscle that can be achieved with optical scattering spectroscopy alone. These data and previous findings with other modalities such as (1) analysis of the image from a fiberoptic neuroendoscope and (2) the output from a microstrain gauge suggest the Smart Probe multiple microsensor technique shows promise for real-time tissue identification in neurosurgical procedures. Copyright 2000 S. Karger AG, Basel.
Document ID
20040141528
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Andrews, R.
(NASA Ames Research Center Moffett Field CA United States)
Mah, R.
Aghevli, A.
Freitas, K.
Galvagni, A.
Guerrero, M.
Papsin, R.
Reed, C.
Stassinopoulos, D.
Date Acquired
August 22, 2013
Publication Date
January 1, 1999
Publication Information
Publication: Stereotactic and functional neurosurgery
Volume: 73
Issue: 1-4
ISSN: 1011-6125
Subject Category
Man/System Technology And Life Support
Distribution Limits
Public
Copyright
Other
Keywords
Non-programmatic

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