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Nutrition and muscle loss in humans during spaceflightThe protein loss in humans during spaceflight is partly due to a normal adaptive response to a decreased work load on the muscles involved in weight bearing. The process is mediated by changes in prostaglandin release, secondary to the decrease in tension on the affected muscles. On missions, where there is a high level of physical demands on the astronauts, there tends to be an energy deficit, which adds to the muscle protein loss and depletes the body fat reserves. While the adaptive response is a normal part of homeostasis, the additional protein loss from an energy deficit can, in the long run, have a negative effect on health and capability of humans to live and work in space and afterward return to Earth.
Document ID
Document Type
Reprint (Version printed in journal)
Stein, T. P. (University of Medicine and Dentistry of New Jersey Stratford, United States)
Date Acquired
August 22, 2013
Publication Date
January 1, 1999
Publication Information
Publication: Advances in space biology and medicine
Volume: 7
ISSN: 1569-2574
Subject Category
Life Sciences (General)
Distribution Limits
NASA Program Biomedical Research and Countermeasures
Non-NASA Center
STS-58 Shuttle Project
NASA Discipline Regulatory Physiology
Flight Experiment
STS Shuttle Project
short duration
STS-40 Shuttle Project
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