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A system for low field imaging of laser-polarized noble gasWe describe a device for performing MRI with laser-polarized noble gas at low magnetic fields (<50 G). The system is robust, portable, inexpensive, and provides gas-phase imaging resolution comparable to that of high field clinical instruments. At 20.6 G, we have imaged laser-polarized (3)He (Larmor frequency of 67 kHz) in both sealed glass cells and excised rat lungs, using approximately 0.1 G/cm gradients to achieve approximately 1 mm(2) resolution. In addition, we measured (3)He T(2)(*) times greater than 100 ms in excised rat lungs, which is roughly 20 times longer than typical values observed at high ( approximately 2 T) fields. We include a discussion of the practical considerations for working at low magnetic fields and conclude with evidence of radiation damping in this system. Copyright 1999 Academic Press.
Document ID
20040141755
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Wong, G. P.
(Harvard-Smithsonian Center for Astrophysics Cambridge, Massachusetts 02138, United States)
Tseng, C. H.
Pomeroy, V. R.
Mair, R. W.
Hinton, D. P.
Hoffmann, D.
Stoner, R. E.
Hersman, F. W.
Cory, D. G.
Walsworth, R. L.
Date Acquired
August 22, 2013
Publication Date
December 1, 1999
Publication Information
Publication: Journal of magnetic resonance (San Diego, Calif. : 1997)
Volume: 141
Issue: 2
ISSN: 1090-7807
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Other
Keywords
NASA Program Biomedical Research and Countermeasures
Non-NASA Center
NASA Discipline Environmental Health

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