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A fluid--structure interaction finite element analysis of pulsatile blood flow through a compliant stenotic arteryA new model is used to analyze the fully coupled problem of pulsatile blood flow through a compliant, axisymmetric stenotic artery using the finite element method. The model uses large displacement and large strain theory for the solid, and the full Navier-Stokes equations for the fluid. The effect of increasing area reduction on fluid dynamic and structural stresses is presented. Results show that pressure drop, peak wall shear stress, and maximum principal stress in the lesion all increase dramatically as the area reduction in the stenosis is increased from 51 to 89 percent. Further reductions in stenosis cross-sectional area, however, produce relatively little additional change in these parameters due to a concomitant reduction in flow rate caused by the losses in the constriction. Inner wall hoop stretch amplitude just distal to the stenosis also increases with increasing stenosis severity, as downstream pressures are reduced to a physiological minimum. The contraction of the artery distal to the stenosis generates a significant compressive stress on the downstream shoulder of the lesion. Dynamic narrowing of the stenosis is also seen, further augmenting area constriction at times of peak flow. Pressure drop results are found to compare well to an experimentally based theoretical curve, despite the assumption of laminar flow.
Document ID
20040141851
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Bathe, M.
(Massachusetts Institute of Technology Cambridge 02139, United States)
Kamm, R. D.
Date Acquired
August 22, 2013
Publication Date
August 1, 1999
Publication Information
Publication: Journal of biomechanical engineering
Volume: 121
Issue: 4
ISSN: 0148-0731
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Other
Keywords
Non-NASA Center
NASA Discipline Cardiopulmonary

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