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Developmental changes in NMDA receptor expression in the platyfish brainWe have examined the distribution of the N-methyl-D-aspartate (NMDA) receptor in the brain of a freshwater teleost using an antibody against the R1 subunit of the receptor (NMDAR1). The primary site of localization was the nucleus olfactoretinalis (NOR), a significant gonadotropin releasing hormone (GnRH)-containing brain nucleus. The number of cells expressing NMDAR1 in this nucleus was dependent upon developmental stage, with pubescent and mature animals displaying significantly more stained cells than immature and senescent animals. This is the first reported observation of age- and maturity-related NMDA receptor association with GnRH-containing brain areas.
Document ID
20040172796
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Flynn, K. M.
(The Graduate School and University Center of the City University of New York NY, United States)
Schreibman, M. P.
Magliulo-Cepriano, L.
Date Acquired
August 22, 2013
Publication Date
October 10, 1997
Publication Information
Publication: Brain research
Volume: 771
Issue: 1
ISSN: 0006-8993
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Other
Keywords
NASA Discipline Developmental Biology
Non-NASA Center

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