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Malignant vagotonia due to selective baroreflex failureBaroreflex failure is characterized by dramatic fluctuations of sympathetic activity and paroxysms of hypertension and tachycardia. In contrast, unopposed parasympathetic activity has not been described in patients with baroreflex failure because of concurrent parasympathetic denervation of the heart. We describe the unusual case of a patient with baroreflex failure in a setting of preserved parasympathetic control of HR manifesting episodes of severe bradycardia and asystole. Thus, parasympathetic control of the HR may be intact in occasional patients with baroreflex failure. Patients with this selective baroreflex failure require a unique therapeutic strategy for the control of disease manifestations.
Document ID
20040172858
Acquisition Source
Legacy CDMS
Document Type
Reprint (Version printed in journal)
Authors
Jordan, J.
(Vanderbilt University Nashville, Tenn 37232-2195, United States)
Shannon, J. R.
Black, B. K.
Costa, F.
Ertl, A. C.
Furlan, R.
Biaggioni, I.
Robertson, D.
Date Acquired
August 22, 2013
Publication Date
November 1, 1997
Publication Information
Publication: Hypertension
Volume: 30
Issue: 5
ISSN: 0194-911X
Subject Category
Aerospace Medicine
Funding Number(s)
CONTRACT_GRANT: RR-00095
CONTRACT_GRANT: NS-33460
Distribution Limits
Public
Copyright
Other
Keywords
Case Reports
Non-NASA Center
NASA Discipline Regulatory Physiology

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