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Genetics and molecular biology of hypotensionMajor strides in the molecular biology of essential hypertension are currently underway. This has tended to obscure the fact that a number of inherited disorders associated with low blood pressure exist and that these diseases may have milder and underrecognized phenotypes that contribute importantly to blood pressure variation in the general population. This review highlights some of the gene products that, if abnormal, could cause hypotension in some individuals. Diseases due to abnormalities in the catecholamine enzymes are discussed in detail. It is likely that genetic abnormalities with hypotensive phenotypes will be as interesting and diverse as those that give rise to hypertensive disorders.
Document ID
20050000401
Document Type
Reprint (Version printed in journal)
Authors
Robertson, D.
(Clinical Research Center, Vanderbilt University Nashville, TN 37232-2195)
Date Acquired
August 22, 2013
Publication Date
January 1, 1994
Publication Information
Publication: Current opinion in nephrology and hypertension
Volume: 3
Issue: 1
ISSN: 1062-4821
Subject Category
Life Sciences (General)
Distribution Limits
Public
Copyright
Other
Keywords
Review, Academic
NASA Discipline Regulatory Physiology
Review
Non-NASA Center
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