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Use of lower body negative pressure to counter symptoms of orthostatic intolerance in patients, bed rest subjects, and astronautsThis report briefly discusses some aspects of autonomic cardiovascular dysfunction as related to changes in orthostatic function in patients, bed rest subjects, and astronauts. This relationship is described in normal individuals to provide the basis for discussion of parameters that may be altered in patients, bed rest subjects, and astronauts. The relationships between disease states, age, periods of weightlessness during space flight, and autonomic dysfunction, and their contribution to changes in orthostatic tolerance are presented. The physiologic effects of lower body negative pressure are illustrated by presenting data obtained in bed rest subjects and in astronauts. Finally, the usefulness of lower body negative pressure to counter symptoms of orthostatic intolerance in patients, bed rest subjects, and astronauts is discussed.
Document ID
20050000419
Acquisition Source
Johnson Space Center
Document Type
Reprint (Version printed in journal)
Authors
Lathers, C. M.
(NASA Johnson Space Center Houston, TX United States)
Charles, J. B.
Date Acquired
August 22, 2013
Publication Date
November 1, 1993
Publication Information
Publication: Journal of clinical pharmacology
Volume: 33
Issue: 11
ISSN: 0091-2700
Subject Category
Aerospace Medicine
Distribution Limits
Public
Copyright
Other
Keywords
Review, Tutorial
NASA Discipline Cardiopulmonary
NASA Center JSC
Review

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