NASA Logo, External Link
Facebook icon, External Link to NASA STI page on Facebook Twitter icon, External Link to NASA STI on Twitter YouTube icon, External Link to NASA STI Channel on YouTube RSS icon, External Link to New NASA STI RSS Feed AddThis share icon
 

Record Details

Record 83 of 4191
The role of cytokines in immune changes induced by spaceflight
Author and Affiliation:
Sonnenfeld, G.(School of Medicine, University of Louisville, Department of Microbiology and Immunology, Kentucky 40292)
Miller, E. S.
Abstract: It has become apparent that spaceflight alters many immune responses. Among the regulatory components of the immune response that have been shown to be affected by spaceflight is the cytokine network. Spaceflight, as well as model systems of spaceflight, have been shown to affect the production and action of various cytokines including interferons, interleukins, colony stimulating factors, and tumor necrosis factors. These changes have been shown not to involve a general shutdown of the cytokine network but, rather, to involve selective alterations of specific cytokine functions by spaceflight. The full breadth of changes in cytokines induced by spaceflight, as well as mechanisms, duration, adaptation, reversibility, and significance to resistance to infection and neoplastic diseases, remains to be established.
Publication Date: Sep 01, 1993
Document ID:
20050000426
(Acquired Jan 06, 2005)
Subject Category: AEROSPACE MEDICINE
Document Type: Journal Article
Publication Information: Journal of leukocyte biology (ISSN 0741-5400); Volume 54; 3; 253-8
Publisher Information: United States
Description: In English
Distribution Limits: Unclassified; Publicly available; Unlimited
Rights: Copyright
NASA Terms: IMMUNE SYSTEMS; SPACE FLIGHT; AEROSPACE MEDICINE; BIOASTRONAUTICS; COSMOS SATELLITES; RATS; SPACE SHUTTLE MISSIONS
Other Descriptors: CYTOKINES/PHYSIOLOGY; IMMUNE SYSTEM/PHYSIOLOGY; SPACE FLIGHT; ANIMALS; HUMAN; RATS; SUPPORT, U.S. GOV'T, NON-P.H.S; NASA DISCIPLINE NUMBER 00-00; NASA DISCIPLINE NUMBER 18-10; NASA DISCIPLINE REGULATORY PHYSIOLOGY; NASA EXPERIMENT NUMBER COS 2044-35; NASA PROGRAM FLIGHT; NASA PROGRAM SPACE PHYSIOLOGY AND COUNTERMEASURES; NON-NASA CENTER; COSMOS 1887 PROJECT; COSMOS 2044 PROJECT; FLIGHT EXPERIMENT; STS SHUTTLE PROJECT; MANNED; SHORT DURATION; UNMANNED
Availability Source: Other Sources
› Back to Top
Find Similar Records
NASA Logo, External Link
NASA Official: Gerald Steeman
Site Curator: STI Program
Last Modified: August 23, 2011
Contact Us