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Conventional heart rate variability analysis of ambulatory electrocardiographic recordings fails to predict imminent ventricular fibrillationOBJECTIVES. The purpose of this report was to study heart rate variability in Holter recordings of patients who experienced ventricular fibrillation during the recording. BACKGROUND. Decreased heart rate variability is recognized as a long-term predictor of overall and arrhythmic death after myocardial infarction. It was therefore postulated that heart rate variability would be lowest when measured immediately before ventricular fibrillation. METHODS. Conventional indexes of heart rate variability were calculated from Holter recordings of 24 patients with structural heart disease who had ventricular fibrillation during monitoring. The control group consisted of 19 patients with coronary artery disease, of comparable age and left ventricular ejection fraction, who had nonsustained ventricular tachycardia but no ventricular fibrillation. RESULTS. Heart rate variability did not differ between the two groups, and no consistent trends in heart rate variability were observed before ventricular fibrillation occurred. CONCLUSIONS. Although conventional heart rate variability is an independent long-term predictor of adverse outcome after myocardial infarction, its clinical utility as a short-term predictor of life-threatening arrhythmias remains to be elucidated.
Document ID
20050000442
Document Type
Reprint (Version printed in journal)
Authors
Vybiral, T. (Baylor College of Medicine Houston, Texas)
Glaeser, D. H.
Goldberger, A. L.
Rigney, D. R.
Hess, K. R.
Mietus, J.
Skinner, J. E.
Francis, M.
Pratt, C. M.
Date Acquired
August 22, 2013
Publication Date
August 1, 1993
Publication Information
Publication: Journal of the American College of Cardiology
Volume: 22
Issue: 2
ISSN: 0735-1097
Subject Category
Life Sciences (General)
Funding Number(s)
CONTRACT_GRANT: R01 HL
CONTRACT_GRANT: P30-AG08812
CONTRACT_GRANT: P01-DA06316
Distribution Limits
Public
Copyright
Other
Keywords
Non-NASA Center
NASA Discipline Cardiopulmonary