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Sympathoinhibition and hypotension in carotid sinus hypersensitivityCarotid sinus reflex hypersensitivity is a known cause of syncope in humans. The condition is characterized by cardioinhibition and vasodepression, each to varying degrees. The extent and importance of sympathoinhibition has not been determined in patients with carotid sinus hypersensitivity. This study reports on the extent of sympathoinhibition measured directly directly during carotid massage with and without atrioventricular sequential pacing, in a patient with symptomatic carotid sinus reflex hypersensitivity. Carotid massage elicited asystole, hypotension and complete inhibition of muscle sympathetic nerve activity. Carotid massage during atrioventricular pacing produced similar sympathoinhibition, but with minimal hypotension. Therefore, sympathoinhibition did not contribute importantly to the hypotension during carotid massage in the supine position in this patient. Further investigations are required to elucidate the relation of sympathoinhibition to hypotension in patients with carotid sinus hypersensitivity in the upright position.
Document ID
20050000562
Document Type
Reprint (Version printed in journal)
External Source(s)
Authors
Smith, M. L.
(Hunter Holmes McGuire Department of Veterans Affairs Medical Center Richmond 23249)
Ellenbogen, K. A.
Eckberg, D. L.
Date Acquired
August 22, 2013
Publication Date
December 1, 1992
Publication Information
Publication: Clinical autonomic research : official journal of the Clinical Autonomic Research Society
Volume: 2
Issue: 6
ISSN: 0959-9851
Subject Category
Aerospace Medicine
Funding Number(s)
CONTRACT_GRANT: HL-07556
CONTRACT_GRANT: HL-22296
Distribution Limits
Public
Copyright
Other
Keywords
Non-NASA Center
Case Reports
NASA Discipline Cardiopulmonary

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