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Record Details

Record 1 of 1991
In vivo assessment of forearm bone mass and ulnar bending stiffness in healthy men
Author and Affiliation:
Myburgh, K. H.(Musculoskeletal Research Laboratory, VA Medical Center, Palo Alto, California)
Zhou, L. J.
Steele, C. R.
Arnaud, S.
Marcus, R.
Abstract: The cross-sectional bending stiffness EI of the ulna was measured in vivo by mechanical resistance tissue analysis (MRTA) in 90 men aged 19-89 years. MRTA measures the impedance response of low-frequency vibrations to determine EI, which is a reflection of elastic modulus E and moment of inertia I for the whole ulna. EI was compared to conventional estimates of bone mineral content (BMC), bone width (BW), and BMC/BW, which were all measured by single-photon absorptiometry. Results obtained from the nondominant ulna indicate that BW increases (r = 0.27, p = 0.01) and ulnar BMC/BW decreases (r = -0.31, p < or = 0.005) with age. Neither BMC nor EI declined with age. The single best predictor of EI was BW (r2 = 0.47, p = 0.0001), and further small but significant contributions were made by BMC (r2 = 0.53, p = 0.0001) and grip strength (r2 = 0.55, p = 0.0001). These results suggest that the resistance of older men to forearm fracture is related to age-associated changes in the moment of inertia achieved by redistributing bone mineral farther from the bending axis. We conclude that the in vivo assessment of bone geometry offers important insights to the comprehensive evaluation of bone strength.
Publication Date: Nov 01, 1992
Document ID:
20050000575
(Acquired Jan 06, 2005)
Subject Category: AEROSPACE MEDICINE
Document Type: Journal Article
Publication Information: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research (ISSN 0884-0431); Volume 7; 11; 1345-50
Publisher Information: United States
Financial Sponsor: NASA Ames Research Center; Moffett Field, CA United States
Description: In English
Distribution Limits: Unclassified; Publicly available; Unlimited
Rights: Copyright
NASA Terms: AGING; BENDING; BONE MINERAL CONTENT; BONES; FOREARM; HUMAN BEINGS; IN VIVO METHODS AND TESTS; MALES; STIFFNESS; ULNA; ADULTS; AGE FACTOR; BIODYNAMICS; PHOTON ABSORPTIOMETRY
Other Descriptors: AGING/PHYSIOLOGY; BONE DENSITY/PHYSIOLOGY; ULNA/PHYSIOLOGY; ABSORPTIOMETRY, PHOTON; ADULT; AGED; AGED, 80 AND OVER; BIOMECHANICS; FOREARM; HUMAN; MALE; MIDDLE AGED; SUPPORT, U.S. GOV'T, NON-P.H.S; NASA CENTER ARC; NASA DISCIPLINE MUSCULOSKELETAL
Availability Source: Other Sources
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