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Record 4 of 4422
Hit rates and radiation doses to nuclei of bone lining cells from alpha-particle-emitting radionuclides
Author and Affiliation:
Polig, E.(Kernforschungszentrum Karlsruhe, Institut fur Genetik und fur Toxikologie von Spaltstoffen, Germany)
Jee, W. S.
Kruglikov, I. L.
Abstract: Factors relating the local concentration of a bone-seeking alpha-particle emitter to the mean hit rate have been determined for nuclei of bone lining cells using a Monte Carlo procedure. Cell nuclei were approximated by oblate spheroids with dimensions and location taken from a previous histomorphometric study. The Monte Carlo simulation is applicable for planar and diffuse labels at plane or cylindrical bone surfaces. Additionally, the mean nuclear dose per hit, the dose mean per hit, the mean track segment length and its second moment, the percentage of stoppers, and the frequency distribution of the dose have been determined. Some basic features of the hit statistics for bone lining cells have been outlined, and the consequences of existing standards of radiation protection with regard to the hit frequency to cell nuclei are discussed.
Publication Date: Aug 01, 1992
Document ID:
20050000624
(Acquired Jan 06, 2005)
Subject Category: LIFE SCIENCES (GENERAL)
Document Type: Journal Article
Publication Information: Radiation research; p. 133-42; (ISSN 0033-7587); Volume 131; 2
Publisher Information: United States
Description: In English
Distribution Limits: Unclassified; Publicly available; Unlimited
Rights: Copyright
NASA Terms: ALPHA PARTICLES; BONES; DOSAGE; LININGS; NUCLEI (CYTOLOGY); PLUTONIUM; RADIOACTIVE ISOTOPES; DOGS; MONTE CARLO METHOD; RADIATION DOSAGE
Other Descriptors: ALPHA PARTICLES; BONE AND BONES/CYTOLOGY; CELL NUCLEUS/RADIATION EFFECTS; PLUTONIUM; ANIMALS; DOGS; HUMAN; MONTE CARLO METHOD; RADIATION DOSAGE; SUPPORT, U.S. GOV'T, NON-P.H.S; NASA DISCIPLINE MUSCULOSKELETAL; NON-NASA CENTER
Availability Source: Other Sources
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