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Blood biochemical and cellular changes during a decompression procedure involving eight hours of oxygen prebreathingChemical and cellular parameters were measured in human subjects before and after exposure to a decompression schedule involving 8 h of oxygen prebreathing. The exposure was designed to simulate space-flight extravehicular activity (EVA) for 6 h. Several statistically significant changes in blood parameters were observed following the exposure: increases in calcium, magnesium, osmolality, low-density lipoprotein cholesterol, monocytes, and prothrombin time, and decreases in chloride, creatine phosphokinase and eosinophils. The changes, however, were small in magnitude and blood factor levels remained within normal clinical ranges. Thus, the decompression profile used in this study is not likely to result in blood changes that would pose a threat to astronauts during EVA.
Document ID
Document Type
Reprint (Version printed in journal)
Jauchem, J. R. (NASA Johnson Space Center Houston, TX United States)
Date Acquired
August 22, 2013
Publication Date
January 1, 1989
Publication Information
Publication: Clinical physiology and biochemistry
Volume: 7
Issue: 1
ISSN: 0252-1164
Subject Category
Life Sciences (General)
Distribution Limits