NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Back to Results
Robust Bioinformatics Recognition with VLSI Biochip MicrosystemA microsystem architecture for real-time, on-site, robust bioinformatic patterns recognition and analysis has been proposed. This system is compatible with on-chip DNA analysis means such as polymerase chain reaction (PCR)amplification. A corresponding novel artificial neural network (ANN) learning algorithm using new sigmoid-logarithmic transfer function based on error backpropagation (EBP) algorithm is invented. Our results show the trained new ANN can recognize low fluorescence patterns better than the conventional sigmoidal ANN does. A differential logarithmic imaging chip is designed for calculating logarithm of relative intensities of fluorescence signals. The single-rail logarithmic circuit and a prototype ANN chip are designed, fabricated and characterized.
Document ID
20070018082
Acquisition Source
Jet Propulsion Laboratory
Document Type
Preprint (Draft being sent to journal)
External Source(s)
Authors
Lue, Jaw-Chyng L.
(University of Southern California Los Angeles, CA, United States)
Fang, Wai-Chi
(Jet Propulsion Lab., California Inst. of Tech. Pasadena, CA, United States)
Date Acquired
August 23, 2013
Publication Date
July 13, 2006
Subject Category
Electronics And Electrical Engineering
Meeting Information
Meeting: IEEE/NLM Life Science Systems and Applications Workshop
Location: Bethesda, MD
Country: United States
Start Date: July 13, 2006
End Date: July 14, 2006
Sponsors: National Library of Medicine, Institute of Electrical and Electronics Engineers
Distribution Limits
Public
Copyright
Other
Keywords
bioinformatics
Very Large-Scale Integration (VLSI)

Available Downloads

There are no available downloads for this record.
No Preview Available