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Fat-Soluble Vitamin Status in Self-Neglecting ElderlyElder self-neglect is a form of elder mistreatment. The systematic characterization of self-neglecting individuals is the goal of the CREST project. Reported here is the evaluation of fat-soluble vitamin status. Self-neglect (SN) subjects were recruited and consented following referral from Adult Protective Services. Control (CN) subjects were matched for age, gender, race, and socioeconomic status, as possible. We report here on 47 SN subjects (age 77 plus or minus 7, mean plus or minus SD; body weight 76 kg plus or minus 26) and 40 CN subjects (77 y plus or minus 7, 79 kg plus or minus 20). Blood samples were analyzed for indices of fat-soluble vitamin status. Plasma retinol (p less than 0.01) was lower in SN subjects. Plasma tocopherol tended (p less than 0.06) to be lower in SN subjects, while gamma-tocopherol was unchanged. SN subjects tended to have lower serum 25-OH vitamin D (p less than 0.11), and to be vitamin D deficient (26% below 23 mmol/L). Hypercalcemia occurred more often in SN subjects (23% had values above 2.56 mmol/L), as did elevated parathyroid hormone concentrations (p less than 0.05). These data demonstrate that many nutrients are affected in the self-neglecting elderly, and that long-term deficits are evident by the nature of changes in fat soluble vitamins.
Document ID
20080026089
Acquisition Source
Johnson Space Center
Document Type
Conference Paper
Authors
Kala, G.
(Enterprise Advisory Services, Inc. Houston, TX, United States)
Oliver, S. Mathews
(Enterprise Advisory Services, Inc. Houston, TX, United States)
Kelly, P. A.
(Baylor Coll. of Medicine Houston, TX, United States)
Pickens, S.
(Baylor Coll. of Medicine Houston, TX, United States)
Burnett, J.
(Baylor Coll. of Medicine Houston, TX, United States)
Dyer, C. B.
(Baylor Coll. of Medicine Houston, TX, United States)
Smith, S. M.
(NASA Johnson Space Center Houston, TX, United States)
Date Acquired
August 24, 2013
Publication Date
April 1, 2006
Subject Category
Life Sciences (General)
Meeting Information
Meeting: Experimental Biology
Location: San Francisco, CA
Country: United States
Start Date: April 1, 2006
End Date: April 5, 2006
Sponsors: Federation of American Societies for Experimental Biology
Funding Number(s)
CONTRACT_GRANT: NIH P20-RR020626-02
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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