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VESsel GENeration Analysis (VESGEN): Innovative Vascular Mappings for Astronaut Exploration Health Risks and Human Terrestrial MedicineCurrently, astronauts face significant health risks in future long-duration exploration missions such as colonizing the Moon and traveling to Mars. Numerous risks include greatly increased radiation exposures beyond the low earth orbit (LEO) of the ISS, and visual and ocular impairments in response to microgravity environments. The cardiovascular system is a key mediator in human physiological responses to radiation and microgravity. Moreover, blood vessels are necessarily involved in the progression and treatment of vascular-dependent terrestrial diseases such as cancer, coronary vessel disease, wound-healing, reproductive disorders, and diabetes. NASA developed an innovative, globally requested beta-level software, VESsel GENeration Analysis (VESGEN) to map and quantify vascular remodeling for application to astronaut and terrestrial health challenges. VESGEN mappings of branching vascular trees and networks are based on a weighted multi-parametric analysis derived from vascular physiological branching rules. Complex vascular branching patterns are determined by biological signaling mechanisms together with the fluid mechanics of multi-phase laminar blood flow.
Document ID
20170012213
Acquisition Source
Ames Research Center
Document Type
Presentation
Authors
Parsons-Wingerter, Patricia
(NASA Ames Research Center Moffett Field, CA, United States)
Kao, David
(NASA Ames Research Center Moffett Field, CA, United States)
Valizadegan, Hamed
(Universities Space Research Association Moffett Field, CA, United States)
Martin, Rodney
(NASA Ames Research Center Moffett Field, CA, United States)
Murray, Matthew C.
(Blue Marble Space Seattle, WA, United States)
Ramesh, Sneha
(Blue Marble Space Seattle, WA, United States)
Sekaran, Srinivaas
(Blue Marble Space Seattle, WA, United States)
Date Acquired
December 18, 2017
Publication Date
September 28, 2017
Subject Category
Aerospace Medicine
Lunar And Planetary Science And Exploration
Report/Patent Number
ARC-E-DAA-TN47140
Meeting Information
Meeting: Ames Research and Technology Showcase (ARTS)
Location: Moffett Field, CA
Country: United States
Start Date: September 28, 2017
Sponsors: NASA Ames Research Center
Funding Number(s)
CONTRACT_GRANT: NNA16BD14C
CONTRACT_GRANT: NNX15AG98A
Distribution Limits
Public
Copyright
Public Use Permitted.
Keywords
astronaut
vascular
machine learnin
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