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Factors modifying the response of large animals to low-intensity radiation exposureIn assessing the biological response to space radiation, two of the most important modifying factors are dose protraction and dose distribution to the body. Studies are reported in which sheep and swine were used to compare the hematology and lethality response resulting from radiation exposure encountered in a variety of forms, including acute (high dose-rate), chronic (low dose-rate), combinations of acute and chronic, and whether received as a continuous or as fractionated exposure. While sheep and swine are basically similar in response to acute radiation, their sensitivity to chronic irradiation is markedly different. Sheep remain relatively sensitive as the radiation exposure is protracted while swine are more resistant and capable of surviving extremely large doses of chronic irradiation. This response to chronic irradiation correlated well with changes in radiosensitivity and recovery following an acute, sublethal exposure.
Document ID
Document Type
Conference Paper
Page, N. P. (National Cancer Inst. Bethesda, MD, United States)
Still, E. T. (AEC Washington, D. C., United States)
Date Acquired
August 6, 2013
Publication Date
January 1, 1972
Publication Information
Publication: NASA, Washington Proc. of the Natl. Symp. on Nat. and Manmade Radiation in Space
Subject Category
Distribution Limits
Work of the US Gov. Public Use Permitted.

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IDRelationTitle19720009951Analytic PrimaryProceedings of the National Symposium on Natural and Manmade Radiation in Space