Radiation carcinogenesis and acute radiation mortality in the rat as produced by 2.2 GeV protonsBiological studies, proton carcinogenesis, the interaction of protons and gamma-rays on carcinogenesis, proton-induced acute mortality, and chemical protection against proton-induced acute mortality were studied in the rat and these proton-produced responses were compared to similar responses produced by gamma-rays or X-rays. Litter-mate mice were assigned to each experimental and control group so that approximately equal numbers of litter mates were placed in each group. Animals to be studied for mammary neoplasia were handled for 365 days post-exposure when all animals alive were killed. All animals were examined frequently for mammary tumors and as these were found, they were removed, sectioned and given a pathologic classification.
Shellabarger, C. J. (Michigan Univ. Ann Arbor, MI, United States)
Straub, R. F. (Michigan Univ. Ann Arbor, MI, United States)
Jesseph, J. E. (Michigan Univ. Ann Arbor, MI, United States)
Montour, J. L. (Michigan Univ. Ann Arbor, MI, United States)
August 6, 2013
January 1, 1972
Publication: NASA, Washington Proc. of the Natl. Symp. on Nat. and Manmade Radiation in Space