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Lymphatic involution and early mortality in the young chicken produced by 2.2 GeV protonsYoung single-comb white Leghorn cockerels were subjected to single acute doses of either 2.2 GeV protons or 250 kVp X-rays. Since young chickens exposed in the lethal range die within 48 hours of exposure, an hourly tabulation of deaths was recorded for this length of time after exposure. Animals which were exposed to sublethal doses were killed five days after exposure and their major lymphatic organs, (thymus, bursa, and spleen), removed and weighed. In the lethal range, animals exposed to 2.2 GeV protons died sooner than those receiving similar doses of X-rays, but total mortality was similar in each case at similar dose levels. The 48 hour LD sub 50 was determined to be 710 rad. Measured five days after exposure, 50% depression ED sub 50 for lymphatic organs occurred as follows: (1) thymus, 350 rad; (2) pursa, 500 rad, and (3) spleen, 450 rad. In all case R.B.E. values were not different from unity.
Document ID
19720010039
Document Type
Conference Paper
Authors
Montour, J. L. (Michigan Univ. Ann Arbor, MI, United States)
Shellabarger, C. J. (Michigan Univ. Ann Arbor, MI, United States)
Date Acquired
August 6, 2013
Publication Date
January 1, 1972
Publication Information
Publication: NASA, Washington Proc. of the Natl. Symp. on Nat. and Manmade Radiation in Space
Subject Category
BIOSCIENCES
Funding Number(s)
CONTRACT_GRANT: NGR-23-005-009
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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IDRelationTitle19720009951Analytic PrimaryProceedings of the National Symposium on Natural and Manmade Radiation in Space