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Five biomedical experiments flown in an Earth orbiting laboratory: Lessons learned from developing these experiments on the first international microgravity mission from concept to landingThere are numerous problems associated with accommodating complex biological systems in microgravity in the flexible laboratory systems installed in the Orbiter cargo bay. This presentation will focus upon some of the lessons learned along the way from the University laboratory to the IML-1 Microgravity Laboratory. The First International Microgravity Laboratory (IML-1) mission contained a large number of specimens, including: 72 million nematodes, US-1; 3 billion yeast cells, US-2; 32 million mouse limb-bud cells, US-3; and 540 oat seeds (96 planted), FOTRAN. All five of the experiments had to undergo significant redevelopment effort in order to allow the investigator's ideas and objectives to be accommodated within the constraints of the IML-1 mission. Each of these experiments were proposed as unique entities rather than part of the mission, and many procedures had to be modified from the laboratory practice to meet IML-1 constraints. After a proposal is accepted by NASA for definition, an interactive process is begun between the Principal Investigator and the developer to ensure a maximum science return. The success of the five SLSPO-managed experiments was the result of successful completion of all preflight biological testing and hardware verification finalized at the KSC Life Sciences Support Facility housed in Hangar L. The ESTEC Biorack facility housed three U.S. experiments (US-1, US-2, and US-3). The U.S. Gravitational Plant Physiology Facility housed GTHRES and FOTRAN. The IML-1 mission (launched from KSC on 22 Jan. 1992, and landed at Dryden Flight Research Facility on 30 Jan. 1992) was an outstanding success--close to 100 percent of the prelaunch anticipated science return was achieved and, in some cases, greater than 100 percent was achieved (because of an extra mission day).
Document ID
19940007084
Document Type
Conference Paper
Authors
Winget, C. M. (NASA Ames Research Center Moffett Field, CA, United States)
Lashbrook, J. J. (NASA Ames Research Center Moffett Field, CA, United States)
Callahan, P. X. (NASA Ames Research Center Moffett Field, CA, United States)
Schaefer, R. L. (Lockheed Engineering and Sciences Co. Moffett Field, CA., United States)
Date Acquired
September 6, 2013
Publication Date
February 1, 1993
Publication Information
Publication: NASA. Johnson Space Center, Sixth Annual Workshop on Space Operations Applications and Research (SOAR 1992), Volume 2
Subject Category
LIFE SCIENCES (GENERAL)
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.

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IDRelationTitle19940007055Analytic PrimarySixth Annual Workshop on Space Operations Applications and Research (SOAR 1992), volume 2