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Micro-organ deviceA method for fabricating a micro-organ device comprises providing a microscale support having one or more microfluidic channels and one or more micro-chambers for housing a micro-organ and printing a micro-organ on the microscale support using a cell suspension in a syringe controlled by a computer-aided tissue engineering system, wherein the cell suspension comprises cells suspended in a solution containing a material that functions as a three-dimensional scaffold. The printing is performed with the computer-aided tissue engineering system according to a particular pattern. The micro-organ device comprises at least one micro-chamber each housing a micro-organ; and at least one microfluidic channel connected to the micro-chamber, wherein the micro-organ comprises cells arranged in a configuration that includes microscale spacing between portions of the cells to facilitate diffusion exchange between the cells and a medium supplied from the at least one microfluidic channel.
Document ID
20130009051
Acquisition Source
Headquarters
Document Type
Other - Patent
Authors
Gonda, Steve R.
von Gustedt-Gonda, legal representative, Iris
Chang, Robert C.
Starly, Binil
Culbertson, Christopher
Holtorf, Heidi L.
Sun, Wei
Leslie, Julia
Date Acquired
August 27, 2013
Publication Date
January 1, 2013
Subject Category
Life Sciences (General)
Report/Patent Number
Patent Number: US-Patent-8,343,740
Patent Application Number: US-Patent-Appl-SN-12/058,227
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
Patent
US-Patent-8,343,740
Patent Application
US-Patent-Appl-SN-12/058,227
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