NASA Logo

NTRS

NTRS - NASA Technical Reports Server

Press Enter or click the Search button to begin your search.

Back to Results
Micro-Organ DeviceA method for fabricating a micro-organ device comprises providing a microscale support having one or more microfluidic channels and one or more micro-chambers for housing a micro-organ and printing a micro-organ on the microscale support using a cell suspension in a syringe controlled by a computer-aided tissue engineering system, wherein the cell suspension comprises cells suspended in a solution containing a material that functions as a three-dimensional scaffold. The printing is performed with the computer-aided tissue engineering system according to a particular pattern. The micro-organ device comprises at least one micro-chamber each housing a micro-organ; and at least one microfluidic channel connected to the micro-chamber, wherein the micro-organ comprises cells arranged in a configuration that includes microscale spacing between portions of the cells to facilitate diffusion exchange between the cells and a medium supplied from the at least one microfluidic channel.
Document ID
20150003150
Acquisition Source
Headquarters
Document Type
Other - Patent
Authors
Gonda, Steve R.
Chang, Robert C.
Starly, Binil
Culbertson, Christopher
Holtorf, Heidi L.
Sun, Wei
Leslie, Julia
Date Acquired
March 18, 2015
Publication Date
November 12, 2013
Subject Category
Life Sciences (General)
Report/Patent Number
Patent Application Number: US-Patent-Appl-SN-13/688,982
Patent Number: US-Patent-8,580,546
Distribution Limits
Public
Copyright
Work of the US Gov. Public Use Permitted.
Patent
US-Patent-8,580,546
Patent Application
US-Patent-Appl-SN-13/688,982
No Preview Available