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An Integrated Model of the Cardiovascular and Central Nervous Systems for Analysis of Microgravity Induced Fluid RedistributionA recognized side effect of prolonged microgravity exposure is visual impairment and intracranial pressure (VIIP) syndrome. The medical understanding of this phenomenon is at present preliminary, although it is hypothesized that the headward shift of bodily fluids in microgravity may be a contributor. Computational models can be used to provide insight into the origins of VIIP. In order to further investigate this phenomenon, NASAs Digital Astronaut Project (DAP) is developing an integrated computational model of the human body which is divided into the eye, the cerebrovascular system, and the cardiovascular system. This presentation will focus on the development and testing of the computational model of an integrated model of the cardiovascular system (CVS) and central nervous system (CNS) that simulates the behavior of pressures, volumes, and flows within these two physiological systems.
Document ID
Acquisition Source
Glenn Research Center
Document Type
Price, R.
(Columbia Univ. New York, NY, United States)
Gady, S.
(Whitworth Univ. Spokane, WA, United States)
Heinemann, K.
(Minnesota Univ. Minneapolis, MN, United States)
Nelson, E. S.
(NASA Glenn Research Center Cleveland, OH, United States)
Mulugeta, L.
(Universities Space Research Association Houston, TX, United States)
Ethier, C. R.
(Georgia Inst. of Tech. Atlanta, GA, United States)
Samuels, B. C.
(Alabama Univ. Birmingham, AL, United States)
Feola, A.
(Georgia Inst. of Tech. Atlanta, GA, United States)
Vera, J.
(NASA Glenn Research Center Cleveland, OH, United States)
Myers, J. G.
(NASA Glenn Research Center Cleveland, OH, United States)
Date Acquired
April 2, 2015
Publication Date
January 13, 2015
Subject Category
Aerospace Medicine
Report/Patent Number
Meeting Information
Meeting: 2015 Human Research Program Investigators'' Workshop
Location: Galveston, TX
Country: United States
Start Date: January 13, 2015
End Date: January 15, 2015
Sponsors: NASA Headquarters
Funding Number(s)
WBS: WBS 516724.01.02.10
Distribution Limits
Public Use Permitted.
Space Adaptation Syndrome
Microgravity Fluid Shifts
Space Physiology
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